Clp Protease

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== Function ==
== Function ==
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'''Clp protease''' (CLP) is a serine peptidase which hydrolyzes proteins in the presence of ATP and Mg+2 ion. CLP is found in mitochondria. CLP participates in degradation of misfolded proteins. For more details see <br />
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'''Clp protease''' (CLP) is a serine peptidase which hydrolyzes proteins in the presence of ATP and Mg+2 ion. CLP is found in mitochondria. CLP participates in degradation of misfolded proteins.<ref>PMID:2197275</ref><br />
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For more details see <br />
* [[Clp protease]]
* [[Clp protease]]
* [[Molecular Playground/ClpP]].
* [[Molecular Playground/ClpP]].

Revision as of 11:37, 8 December 2015

E. coli Clp protease catalytic subunit (PDB entry 1tyf)

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3D structures of Clp protease

Updated on 08-December-2015

References

  1. Maurizi MR, Clark WP, Katayama Y, Rudikoff S, Pumphrey J, Bowers B, Gottesman S. Sequence and structure of Clp P, the proteolytic component of the ATP-dependent Clp protease of Escherichia coli. J Biol Chem. 1990 Jul 25;265(21):12536-45. PMID:2197275

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Michal Harel, Alexander Berchansky

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