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5em9
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal 5HT4(a)R PDZ binding motif== | |
| - | + | <StructureSection load='5em9' size='340' side='right' caption='[[5em9]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5em9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EM9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EM9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4z8j|4z8j]], [[5elq|5elq]], [[5ema|5ema]], [[5emb|5emb]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5em9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5em9 OCA], [http://pdbe.org/5em9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5em9 RCSB], [http://www.ebi.ac.uk/pdbsum/5em9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5em9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SNX27_RAT SNX27_RAT]] Involved in endocytic trafficking (By similarity). In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Clairfeuille, T]] | [[Category: Clairfeuille, T]] | ||
| - | [[Category: Collins, B | + | [[Category: Collins, B M]] |
| + | [[Category: Endosome]] | ||
| + | [[Category: Pdz domain]] | ||
| + | [[Category: Protein transport]] | ||
| + | [[Category: Sorting nexin]] | ||
Revision as of 21:04, 10 September 2016
Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal 5HT4(a)R PDZ binding motif
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