1ao7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1ao7.gif|left|200px]]
[[Image:1ao7.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1ao7 |SIZE=350|CAPTION= <scene name='initialview01'>1ao7</scene>, resolution 2.6&Aring;
+
The line below this paragraph, containing "STRUCTURE_1ao7", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=EMC:ETHYL+MERCURY+ION'>EMC</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE= HLA-A 0201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), V BETA 12.3 [BV13S1] - D BETA 2.1 - J BETA 2.1 - ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), V ALPHA 2.3 [AV2S1A2] - J ALPHA 24 - C ALPHA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), V BETA 12.3 [BV13S1] - D BETA 2.1 - J BETA 2.1 - C BETA 2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1ao7| PDB=1ao7 | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ao7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ao7 OCA], [http://www.ebi.ac.uk/pdbsum/1ao7 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ao7 RCSB]</span>
+
-
}}
+
'''COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201'''
'''COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201'''
Line 32: Line 29:
[[Category: Utz, U.]]
[[Category: Utz, U.]]
[[Category: Wiley, D C.]]
[[Category: Wiley, D C.]]
-
[[Category: class i mhc]]
+
[[Category: Class i mhc]]
-
[[Category: complex (mhc/viral peptide/receptor]]
+
[[Category: T-cell receptor]]
-
[[Category: t-cell receptor]]
+
[[Category: Viral peptide]]
-
[[Category: viral peptide]]
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:30:10 2008''
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:44:18 2008''
+

Revision as of 07:30, 2 May 2008

Image:1ao7.gif

Template:STRUCTURE 1ao7

COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201


Overview

Recognition by a T-cell antigen receptor (TCR) of peptide complexed with a major histocompatibility complex (MHC) molecule occurs through variable loops in the TCR structure which bury almost all the available peptide and a much larger area of the MHC molecule. The TCR fits diagonally across the MHC peptide-binding site in a surface feature common to all class I and class II MHC molecules, providing evidence that the nature of binding is general. A broadly applicable binding mode has implications for the mechanism of repertoire selection and the magnitude of alloreactions.

About this Structure

1AO7 is a Protein complex structure of sequences from Homo sapiens and Human t-lymphotropic virus 1. Full crystallographic information is available from OCA.

Reference

Structure of the complex between human T-cell receptor, viral peptide and HLA-A2., Garboczi DN, Ghosh P, Utz U, Fan QR, Biddison WE, Wiley DC, Nature. 1996 Nov 14;384(6605):134-41. PMID:8906788 Page seeded by OCA on Fri May 2 10:30:10 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ao7"
Personal tools