This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4y6m
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Structure of plasmepsin II from Plasmodium falciparum complexed with inhibitor PG418== | ==Structure of plasmepsin II from Plasmodium falciparum complexed with inhibitor PG418== | ||
<StructureSection load='4y6m' size='340' side='right' caption='[[4y6m]], [[Resolution|resolution]] 2.27Å' scene=''> | <StructureSection load='4y6m' size='340' side='right' caption='[[4y6m]], [[Resolution|resolution]] 2.27Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4y6m]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y6M FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4y6m]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y6M FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=48Q:~{N}1-[(~{Z},3~{R})-4-[2-(3-METHOXYPHENYL)PROPAN-2-YLAMINO]-3-OXIDANYL-1-PHENYL-BUT-1-EN-2-YL]-5-PIPERIDIN-1-YL-~{N}3,~{N}3-DIPROPYL-BENZENE-1,3-DICARBOXAMIDE'>48Q</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=48Q:~{N}1-[(~{Z},3~{R})-4-[2-(3-METHOXYPHENYL)PROPAN-2-YLAMINO]-3-OXIDANYL-1-PHENYL-BUT-1-EN-2-YL]-5-PIPERIDIN-1-YL-~{N}3,~{N}3-DIPROPYL-BENZENE-1,3-DICARBOXAMIDE'>48Q</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cku|4cku]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cku|4cku]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y6m OCA], [http://pdbe.org/4y6m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y6m RCSB], [http://www.ebi.ac.uk/pdbsum/4y6m PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y6m OCA], [http://pdbe.org/4y6m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y6m RCSB], [http://www.ebi.ac.uk/pdbsum/4y6m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y6m ProSAT]</span></td></tr> |
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 21: | Line 22: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Plafa]] | ||
[[Category: Plasmepsin II]] | [[Category: Plasmepsin II]] | ||
[[Category: Akopjana, I]] | [[Category: Akopjana, I]] | ||
Revision as of 07:58, 17 January 2018
Structure of plasmepsin II from Plasmodium falciparum complexed with inhibitor PG418
| |||||||||||
