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4rv6

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==Human ARTD1 (PARP1) catalytic domain in complex with inhibitor Rucaparib==
==Human ARTD1 (PARP1) catalytic domain in complex with inhibitor Rucaparib==
<StructureSection load='4rv6' size='340' side='right' caption='[[4rv6]], [[Resolution|resolution]] 3.19&Aring;' scene=''>
<StructureSection load='4rv6' size='340' side='right' caption='[[4rv6]], [[Resolution|resolution]] 3.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rv6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RV6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RV6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rv6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RV6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RV6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RPB:RUCAPARIB'>RPB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RPB:RUCAPARIB'>RPB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4und|4und]], [[4uxb|4uxb]], [[4r5w|4r5w]], [[4r6e|4r6e]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4und|4und]], [[4uxb|4uxb]], [[4r5w|4r5w]], [[4r6e|4r6e]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADPRT, PARP1, PPOL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rv6 OCA], [http://pdbe.org/4rv6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rv6 RCSB], [http://www.ebi.ac.uk/pdbsum/4rv6 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rv6 OCA], [http://pdbe.org/4rv6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rv6 RCSB], [http://www.ebi.ac.uk/pdbsum/4rv6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rv6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Karlberg, T]]
[[Category: Karlberg, T]]
[[Category: Schuler, H]]
[[Category: Schuler, H]]

Revision as of 09:10, 22 November 2017

Human ARTD1 (PARP1) catalytic domain in complex with inhibitor Rucaparib

4rv6, resolution 3.19Å

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