1aqb
From Proteopedia
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'''RETINOL-BINDING PROTEIN (RBP) FROM PIG PLASMA''' | '''RETINOL-BINDING PROTEIN (RBP) FROM PIG PLASMA''' | ||
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[[Category: Panzalorto, M.]] | [[Category: Panzalorto, M.]] | ||
[[Category: Zanotti, G.]] | [[Category: Zanotti, G.]] | ||
| - | [[Category: | + | [[Category: Cadmium ion]] |
| - | [[Category: | + | [[Category: Retinoid]] |
| - | [[Category: | + | [[Category: Retinol transport]] |
| - | [[Category: | + | [[Category: Vitamin some]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:34:51 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 07:34, 2 May 2008
RETINOL-BINDING PROTEIN (RBP) FROM PIG PLASMA
Overview
The crystal structure of pig plasma retinol-binding protein (RBP) has been determined at 1.65 A resolution. The space group is P212121, with a = 45.81 (4), b = 53.14 (5), c = 72.97 (8) A and one protein molecule in the asymmetric unit. The structure has been solved using the molecular replacement method and refined with restrained least squares to an R factor of 0.1844 and an Rfree of 0.237 for 18 874 and 1001 independent reflections, respectively. The relatively high resolution structure of pig holoRBP has revealed some new structural details. Moreover, it has provided a description of the binding site for Cd2+, a metal ion which is required for protein crystallization. The hepta-coordination of the RBP-bound cadmium ion involves different residues of two symmetry-related RBP molecules, consistent with the participation of the cation in intermolecular interactions that in turn promote protein crystallization.
About this Structure
1AQB is a Single protein structure of sequence from Sus scrofa domestica. Full crystallographic information is available from OCA.
Reference
Structure of pig plasma retinol-binding protein at 1.65 A resolution., Zanotti G, Panzalorto M, Marcato A, Malpeli G, Folli C, Berni R, Acta Crystallogr D Biol Crystallogr. 1998 Sep 1;54(Pt 5):1049-52. PMID:9757135 Page seeded by OCA on Fri May 2 10:34:51 2008
