14-3-3 protein

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Line 35: Line 35:
**[[4dat]], [[4dau]] – hPRS + PADI6 peptide <br />
**[[4dat]], [[4dau]] – hPRS + PADI6 peptide <br />
**[[4jc3]], [[4jdd]] – hPRS + estrogen receptor peptide <br />
**[[4jc3]], [[4jdd]] – hPRS + estrogen receptor peptide <br />
-
**[[4fl5]] – hPRS + τ protein peptide <br />
+
**[[4fl5]], [[5btv]], [[5hf3]], [[4y5i]], [[4y32]], [[4y3b]] – hPRS + τ protein peptide <br />
 +
**[[5ltw]] – hPRS (mutant) + HSPB6 <br />
 +
**[[5lu1]], [[5lu2]] – hPRS (mutant) + HSPB6 peptide<br />
 +
**[[4qli]] – hPRS + SNAI1 peptide <br />
*14-3-3 protein σ binary complex with small molecule
*14-3-3 protein σ binary complex with small molecule
Line 46: Line 49:
**[[3p1o]], [[3ux0]], [[4fr3]] – hPRS + TASK-3 peptide + stabilizer<br />
**[[3p1o]], [[3ux0]], [[4fr3]] – hPRS + TASK-3 peptide + stabilizer<br />
-
**[[3p1q]], [[3p1s]], [[3spr]], [[3smk]], [[3sml]], [[3smm]], [[3smn]], [[3smo]] – hPRS (mutant) + TASK-3 peptide + stabilizer<br />
+
**[[3p1q]], [[3p1s]], [[3spr]], [[3smk]], [[3sml]], [[3smm]], [[3smn]], [[3smo]], [[3sp5]] – hPRS (mutant) + TASK-3 peptide + stabilizer<br />
**[[3iqv]], [[3o8i]] – hPRS + Raf-1 peptide + stabilizer<br />
**[[3iqv]], [[3o8i]] – hPRS + Raf-1 peptide + stabilizer<br />
Line 55: Line 58:
**[[1a38]] – bPRS + R18 peptide <br />
**[[1a38]] – bPRS + R18 peptide <br />
**[[1qja]] – hPRS + phosphopeptide <br />
**[[1qja]] – hPRS + phosphopeptide <br />
 +
**[[4wrq]] – hPRS + Chibby peptide <br />
*14-3-3 protein ζ/δ
*14-3-3 protein ζ/δ
**[[3rdh]] – hPRS <br />
**[[3rdh]] – hPRS <br />
 +
**[[3rdh]] – hPRS/LKB1 <br />
**[[1qjb]] – hPRS + phosphopeptide <br />
**[[1qjb]] – hPRS + phosphopeptide <br />
**[[2c1j]], [[2c1n]] – hPRS + histone H3 peptide <br />
**[[2c1j]], [[2c1n]] – hPRS + histone H3 peptide <br />
-
**[[2o02]], [[4n7g]], [[4n7y]], [[4n84]] – hPRS + exoenzyme S peptide <br />
+
**[[2o02]], [[4n7g]], [[4n7y]], [[4n84]], [[5j31]] – hPRS + exoenzyme S peptide <br />
**[[2v7d]], [[4hkc]] – hPRS + integrin peptide <br />
**[[2v7d]], [[4hkc]] – hPRS + integrin peptide <br />
**[[3cu8]], [[3nkx]], [[4fj3]], [[4ihl]] – hPRS + Raf-1 peptide <br />
**[[3cu8]], [[3nkx]], [[4fj3]], [[4ihl]] – hPRS + Raf-1 peptide <br />
**[[2wh0]] – hPRS + protein kinase C ε peptide <br />
**[[2wh0]] – hPRS + protein kinase C ε peptide <br />
**[[4bg6]] – hPRS + RND3 peptide <br />
**[[4bg6]] – hPRS + RND3 peptide <br />
 +
**[[5ewz]], [[5exa]] – hPRS + GRB2-associated protein peptide <br />
 +
**[[5d2d]] – hPRS + CFTR peptide <br />
 +
**[[5d3f]] – hPRS + CFTR peptide + stabilizer<br />
**[[1ib1]] – hPRS + serotonin N-acetyltransferase <br />
**[[1ib1]] – hPRS + serotonin N-acetyltransferase <br />
Line 75: Line 83:
**[[4j6s]] – hPRS + tyrosine hydroxylase peptide <br />
**[[4j6s]] – hPRS + tyrosine hydroxylase peptide <br />
**[[4o46]] – hPRS + influenza C-terminal peptide <br />
**[[4o46]] – hPRS + influenza C-terminal peptide <br />
 +
**[[5d3e]] – hPRS + CFTR peptide <br />
*14-3-3 protein β/α
*14-3-3 protein β/α
Line 84: Line 93:
*14-3-3 protein θ
*14-3-3 protein θ
 +
**[[5iqp]] – hPRS <br />
**[[2btp]] – hPRS + phosphopeptide <br />
**[[2btp]] – hPRS + phosphopeptide <br />

Revision as of 09:23, 14 February 2017

Structure of human 14-3-3 protein ζ with phosphopeptide (yellow) (PDB code 1qja).

Drag the structure with the mouse to rotate

3D structures of 14-3-3 proteins (Updated on 14-February-2017)

References

  1. Benzinger A, Popowicz GM, Joy JK, Majumdar S, Holak TA, Hermeking H. The crystal structure of the non-liganded 14-3-3sigma protein: insights into determinants of isoform specific ligand binding and dimerization. Cell Res. 2005 Apr;15(4):219-27. PMID:15857576 doi:10.1038/sj.cr.7290290

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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