This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5c0t
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crystal structure of the mercury-bound form of MerB mutant D99S== |
| - | + | <StructureSection load='5c0t' size='340' side='right' caption='[[5c0t]], [[Resolution|resolution]] 1.96Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5c0t]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C0T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3f0p|3f0p]], [[5c0u|5c0u]], [[5c17|5c17]], [[5dsf|5dsf]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkylmercury_lyase Alkylmercury lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.2 4.99.1.2] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c0t OCA], [http://pdbe.org/5c0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c0t RCSB], [http://www.ebi.ac.uk/pdbsum/5c0t PDBsum]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MERB_ECOLX MERB_ECOLX]] Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Alkylmercury lyase]] | ||
[[Category: Cappadocia, L]] | [[Category: Cappadocia, L]] | ||
| - | [[Category: Wahba, H.M]] | ||
| - | [[Category: Wilkinson, K.J]] | ||
[[Category: Lafrance-Vanasse, J]] | [[Category: Lafrance-Vanasse, J]] | ||
| - | [[Category: Wilcox, D.E]] | ||
| - | [[Category: Stevenson, M]] | ||
[[Category: Lecoq, L]] | [[Category: Lecoq, L]] | ||
| - | [[Category: Omichinski, J.G]] | ||
[[Category: Mansour, A]] | [[Category: Mansour, A]] | ||
| + | [[Category: Omichinski, J G]] | ||
| + | [[Category: Stevenson, M]] | ||
[[Category: Sygusch, J]] | [[Category: Sygusch, J]] | ||
| + | [[Category: Wahba, H M]] | ||
| + | [[Category: Wilcox, D E]] | ||
| + | [[Category: Wilkinson, K J]] | ||
| + | [[Category: Bacterial protein]] | ||
| + | [[Category: Cysteine]] | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Lyase]] | ||
| + | [[Category: Mercury]] | ||
| + | [[Category: Metal binding protein]] | ||
| + | [[Category: Mutation]] | ||
Revision as of 15:52, 3 February 2016
Crystal structure of the mercury-bound form of MerB mutant D99S
| |||||||||||
