5ceu

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'''Unreleased structure'''
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==Crystal structure of Rv2837c complexed with 5'-pApA==
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<StructureSection load='5ceu' size='340' side='right' caption='[[5ceu]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
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The entry 5ceu is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ceu]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CEU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CEU FirstGlance]. <br>
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Authors: Wang, F., He, Q., Zhu, D., Liu, S., Gu, L.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cet|5cet]]</td></tr>
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Description:
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ceu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ceu OCA], [http://pdbe.org/5ceu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ceu RCSB], [http://www.ebi.ac.uk/pdbsum/5ceu PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NRNA_MYCTU NRNA_MYCTU]] Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for 2-mers. Also degrades 24-mers. Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP.<ref>PMID:22114320</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Gu, L]]
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[[Category: He, Q]]
[[Category: Liu, S]]
[[Category: Liu, S]]
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[[Category: Zhu, D]]
 
[[Category: Wang, F]]
[[Category: Wang, F]]
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[[Category: He, Q]]
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[[Category: Zhu, D]]
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[[Category: Gu, L]]
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[[Category: C-di-amp]]
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[[Category: Complex]]
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[[Category: Hydrolase-rna complex]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Phosphodiesterase]]

Revision as of 12:48, 23 December 2015

Crystal structure of Rv2837c complexed with 5'-pApA

5ceu, resolution 2.36Å

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