5cw8

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'''Unreleased structure'''
 
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The entry 5cw8 is ON HOLD until Jul 27 2017
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==Crystal structure of Mycobacterium tuberculosis KstR in complex with 3-oxo-4-cholesten-26-oyl-CoA==
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<StructureSection load='5cw8' size='340' side='right' caption='[[5cw8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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Authors: Ho, N.A.T., Dawes, S., Kendall, S., Casabon, I., Crowe, A.M., Baker, E.N., Eltis, L.D., Lott, J.S., TB Structural Genomics Consortium (TBSGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5cw8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CW8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CW8 FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=55X:S-{1-[5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]-3,7-DIHYDROXY-6,6-DIMETHYL-3-OXIDO-8,12-DIOXO-2,4-DIOXA-9,13-DIAZA-3LAMBDA~5~-PHOSPHAPENTADECAN-15-YL}+(2S,6R)-6-[(8S,9S,10R,13R,14S,17R)-10,13-DIMETHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL]-2-METHYLHEPTANETHIOATE+(NON-PREFERRED+NAME)'>55X</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cw8 OCA], [http://pdbe.org/5cw8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cw8 RCSB], [http://www.ebi.ac.uk/pdbsum/5cw8 PDBsum]</span></td></tr>
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[[Category: Lott, J.S]]
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</table>
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[[Category: Ho, N.A.T]]
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== Function ==
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[[Category: Eltis, L.D]]
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[[http://www.uniprot.org/uniprot/KSTR_MYCTU KSTR_MYCTU]] Controls the expression of genes used for utilizing diverse lipids as energy sources.
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[[Category: Kendall, S]]
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__TOC__
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</StructureSection>
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[[Category: Baker, E N]]
[[Category: Casabon, I]]
[[Category: Casabon, I]]
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[[Category: Baker, E.N]]
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[[Category: Crowe, A M]]
[[Category: Dawes, S]]
[[Category: Dawes, S]]
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[[Category: Tb Structural Genomics Consortium (Tbsgc)]]
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[[Category: Eltis, L D]]
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[[Category: Crowe, A.M]]
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[[Category: Ho, N A.T]]
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[[Category: Kendall, S]]
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[[Category: Lott, J S]]
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[[Category: Structural genomic]]
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[[Category: Cholesterol catabolism]]
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[[Category: Coa thioester ligand]]
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[[Category: Tbsgc]]
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[[Category: Tetr family transcriptional repressor]]
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[[Category: Transcription regulator]]
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[[Category: Transcriptional repressor]]

Revision as of 02:52, 21 February 2016

Crystal structure of Mycobacterium tuberculosis KstR in complex with 3-oxo-4-cholesten-26-oyl-CoA

5cw8, resolution 2.60Å

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