5e18
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==T. thermophilus transcription initiation complex having a YYY discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 8 (RPo-CCC-8)== | |
| - | + | <StructureSection load='5e18' size='340' side='right' caption='[[5e18]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5e18]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/ ], [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] and [http://en.wikipedia.org/wiki/Thermus_thermophilus_(strain_hb8_/_atcc_27634_/_dsm_579) Thermus thermophilus (strain hb8 / atcc 27634 / dsm 579)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E18 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E18 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5e17|5e17]]</td></tr> |
| - | [[Category: Ebright, R | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e18 OCA], [http://pdbe.org/5e18 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e18 RCSB], [http://www.ebi.ac.uk/pdbsum/5e18 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RPOC_THET8 RPOC_THET8]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/RPOB_THET8 RPOB_THET8]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/RPOA_THETH RPOA_THETH]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/RPOZ_THET8 RPOZ_THET8]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). [[http://www.uniprot.org/uniprot/Q5SKW1_THET8 Q5SKW1_THET8]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity).[RuleBase:RU000715] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (By similarity).[HAMAP-Rule:MF_00963] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: DNA-directed RNA polymerase]] | ||
| + | [[Category: Thermus thermophilus]] | ||
| + | [[Category: Ebright, R H]] | ||
[[Category: Zhang, Y]] | [[Category: Zhang, Y]] | ||
| + | [[Category: Abortive]] | ||
| + | [[Category: Bacterial]] | ||
| + | [[Category: Consensus]] | ||
| + | [[Category: Discriminator]] | ||
| + | [[Category: Dna]] | ||
| + | [[Category: Dna-directed rna polymerase]] | ||
| + | [[Category: Gene expression regulation]] | ||
| + | [[Category: Promoter region]] | ||
| + | [[Category: Protein conformation]] | ||
| + | [[Category: Rna]] | ||
| + | [[Category: Scrunching]] | ||
| + | [[Category: Sigma]] | ||
| + | [[Category: Sigma factor]] | ||
| + | [[Category: Single-stranded]] | ||
| + | [[Category: Transcription initiation]] | ||
| + | [[Category: Transcription start site]] | ||
| + | [[Category: Transcription-dna-rna complex]] | ||
Revision as of 03:55, 10 March 2016
T. thermophilus transcription initiation complex having a YYY discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 8 (RPo-CCC-8)
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Categories: DNA-directed RNA polymerase | Thermus thermophilus | Ebright, R H | Zhang, Y | Abortive | Bacterial | Consensus | Discriminator | Dna | Dna-directed rna polymerase | Gene expression regulation | Promoter region | Protein conformation | Rna | Scrunching | Sigma | Sigma factor | Single-stranded | Transcription initiation | Transcription start site | Transcription-dna-rna complex
