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5e8p
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==The structure of the TEIPP associated altered peptide ligand Trh4-p5NLE in complex with H-2D(b)== |
| - | + | <StructureSection load='5e8p' size='340' side='right' caption='[[5e8p]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5e8p]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E8P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E8P FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NLE:NORLEUCINE'>NLE</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sphingosine_N-acyltransferase Sphingosine N-acyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.24 2.3.1.24] </span></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e8p OCA], [http://pdbe.org/5e8p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e8p RCSB], [http://www.ebi.ac.uk/pdbsum/5e8p PDBsum]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE]] Involved in the presentation of foreign antigens to the immune system. [[http://www.uniprot.org/uniprot/CERS5_MOUSE CERS5_MOUSE]] Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1.<ref>PMID:12912983</ref> <ref>PMID:16100120</ref> [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Sphingosine N-acyltransferase]] | ||
[[Category: Achour, A]] | [[Category: Achour, A]] | ||
[[Category: Buratto, J]] | [[Category: Buratto, J]] | ||
| - | [[Category: | + | [[Category: Doorduijn, E]] |
| + | [[Category: Duru, A D]] | ||
[[Category: Hafstrand, I]] | [[Category: Hafstrand, I]] | ||
| + | [[Category: Hall, T van]] | ||
| + | [[Category: Oliveira, C C]] | ||
[[Category: Sandalova, T]] | [[Category: Sandalova, T]] | ||
| - | [[Category: | + | [[Category: Cancer]] |
| + | [[Category: Immune system]] | ||
| + | [[Category: Mhc-i]] | ||
| + | [[Category: Neo-epitope]] | ||
| + | [[Category: Non-classical peptide binding]] | ||
| + | [[Category: Sulfur-pi interaction]] | ||
| + | [[Category: Tap-deficiency]] | ||
| + | [[Category: Teipp]] | ||
Revision as of 15:55, 3 February 2016
The structure of the TEIPP associated altered peptide ligand Trh4-p5NLE in complex with H-2D(b)
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