5f4m

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'''Unreleased structure'''
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==Protruding domain of GII.17 norovirus Kawasaki323==
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<StructureSection load='5f4m' size='340' side='right' caption='[[5f4m]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5f4m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F4M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f4j|5f4j]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f4m OCA], [http://pdbe.org/5f4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f4m RCSB], [http://www.ebi.ac.uk/pdbsum/5f4m PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Recent reports suggest that human GII.17 noroviruses are increasing in prevalence. We analyzed the evolutionary changes of three GII.17 capsid protruding (P) domains. We found that the GII.17 P domains had little cross-reactivity with antisera raised against the dominant GII.4 strains. X-ray structural analysis of GII.17 P domains from 2002 to 2014/15 suggested that surface exposed substitutions on the uppermost part of the P domain might have generated a novel 2014/15 GII.17 variant.
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The entry 5f4m is ON HOLD until Paper Publication
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Structural evolution of the emerging 2014/15 GII.17 noroviruses.,Singh BK, Koromyslova A, Hefele L, Gurth C, Hansman GS J Virol. 2015 Dec 23. pii: JVI.03119-15. PMID:26699640<ref>PMID:26699640</ref>
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Authors: Singh, B.K., Hansman, G.S.
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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Description: Protruding domain of GII.17 norovirus Kawasaki323
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<div class="pdbe-citations 5f4m" style="background-color:#fffaf0;"></div>
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[[Category: Unreleased Structures]]
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== References ==
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[[Category: Hansman, G.S]]
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<references/>
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[[Category: Singh, B.K]]
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__TOC__
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</StructureSection>
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[[Category: Hansman, G S]]
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[[Category: Singh, B K]]
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[[Category: Capsid protein]]
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[[Category: Norovirus]]
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[[Category: Protruding domain]]
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[[Category: Viral protein]]

Revision as of 20:02, 13 January 2016

Protruding domain of GII.17 norovirus Kawasaki323

5f4m, resolution 2.27Å

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