5cdo
From Proteopedia
(Difference between revisions)
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==3.15A structure of QPT-1 with S.aureus DNA gyrase and DNA== | ==3.15A structure of QPT-1 with S.aureus DNA gyrase and DNA== | ||
| - | <StructureSection load='5cdo' size='340' side='right' caption='[[5cdo]], [[Resolution|resolution]] 3.15Å' scene=''> | + | <StructureSection load='5cdo' size='340' side='right'caption='[[5cdo]], [[Resolution|resolution]] 3.15Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5cdo]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CDO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CDO FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5cdo]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Staan Staan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CDO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CDO FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=50M:(2R,4S,4AS,5R)-6-HYDROXY-2,4-DIMETHYL-8-NITRO-1,2,4,4A-TETRAHYDRO-2H,6H-SPIRO[1,4-OXAZINO[4,3-A]QUINOLINE-5,5-PYRIMIDINE]-2,4(3H)-DIONE'>50M</scene>, <scene name='pdbligand=53L:(2R,4S,4AS,5S)-6-HYDROXY-2,4-DIMETHYL-8-NITRO-1,2,4,4A-TETRAHYDRO-2H,6H-SPIRO[1,4-OXAZINO[4,3-A]QUINOLINE-5,5-PYRIMIDINE]-2,4(3H)-DIONE'>53L</scene>, <scene name='pdbligand=53M:(2R,4S,4AS)-4,6-DIHYDROXY-2,4-DIMETHYL-8-NITRO-1,2,4,4A-TETRAHYDRO-2H,6H-SPIRO[1,4-OXAZINO[4,3-A]QUINOLINE-5,5-PYRIMIDIN]-2-ONE'>53M</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=50M:(2R,4S,4AS,5R)-6-HYDROXY-2,4-DIMETHYL-8-NITRO-1,2,4,4A-TETRAHYDRO-2H,6H-SPIRO[1,4-OXAZINO[4,3-A]QUINOLINE-5,5-PYRIMIDINE]-2,4(3H)-DIONE'>50M</scene>, <scene name='pdbligand=53L:(2R,4S,4AS,5S)-6-HYDROXY-2,4-DIMETHYL-8-NITRO-1,2,4,4A-TETRAHYDRO-2H,6H-SPIRO[1,4-OXAZINO[4,3-A]QUINOLINE-5,5-PYRIMIDINE]-2,4(3H)-DIONE'>53L</scene>, <scene name='pdbligand=53M:(2R,4S,4AS)-4,6-DIHYDROXY-2,4-DIMETHYL-8-NITRO-1,2,4,4A-TETRAHYDRO-2H,6H-SPIRO[1,4-OXAZINO[4,3-A]QUINOLINE-5,5-PYRIMIDIN]-2-ONE'>53M</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gyrA, SA0006 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158879 STAAN]), gyrB, SA0005 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158879 STAAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cdo OCA], [http://pdbe.org/5cdo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cdo RCSB], [http://www.ebi.ac.uk/pdbsum/5cdo PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cdo OCA], [http://pdbe.org/5cdo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cdo RCSB], [http://www.ebi.ac.uk/pdbsum/5cdo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cdo ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5cdo" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5cdo" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Gyrase 3D Structures|Gyrase 3D Structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staan]] | ||
[[Category: Bax, B D]] | [[Category: Bax, B D]] | ||
[[Category: Chan, P F]] | [[Category: Chan, P F]] | ||
Revision as of 11:34, 27 March 2020
3.15A structure of QPT-1 with S.aureus DNA gyrase and DNA
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