Core-binding factor
From Proteopedia
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== Function == | == Function == | ||
| - | '''Core-binding factor''' (CBF) is a heterodimeric transcription factor which is composed of α chain which binds DNA and a regulatory β chain. CBF binds to various enhancers and promoters including murine leukemia virus and polyomavirus enhancer. <ref>PMID:11276260</ref> | + | '''Core-binding factor''' (CBF) is a heterodimeric transcription factor which is composed of <scene name='70/708082/Cv/2'>α chain which binds DNA and a regulatory β chain</scene>. CBF binds to various enhancers and promoters including murine leukemia virus and polyomavirus enhancer. <ref>PMID:11276260</ref> |
== Disease == | == Disease == | ||
Revision as of 08:48, 21 December 2015
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3D Structures of core-binding factor
Updated on 21-December-2015
References
- ↑ Bravo J, Li Z, Speck NA, Warren AJ. The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp. Nat Struct Biol. 2001 Apr;8(4):371-8. PMID:11276260 doi:http://dx.doi.org/10.1038/86264
