Laccase

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oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional structure of CotA [[1w6l]] comprises three cupredoxin domains and four copper ions organised in <scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>:
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional structure of CotA [[1w6l]] comprises three cupredoxin domains and four copper ions organised in <scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>:
a <scene name='40/404916/Cv/3'>mononuclear blue type 1 copper center</scene> and <scene name='40/404916/Cv/2'>a trinuclear center</scene>.<ref>PMID:11514528</ref><ref>PMID:16234932</ref>
a <scene name='40/404916/Cv/3'>mononuclear blue type 1 copper center</scene> and <scene name='40/404916/Cv/2'>a trinuclear center</scene>.<ref>PMID:11514528</ref><ref>PMID:16234932</ref>
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For laccase with nitrotyrosine modification see [[Nitrotyrosine]].
== Structural highlights ==
== Structural highlights ==
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**[[1nps]] – CotSl N terminal – ''Myxococcus xanthus''
**[[1nps]] – CotSl N terminal – ''Myxococcus xanthus''
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*Laccase
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**[[3div]] - Lac - ''Cerrena maxima''<br />
*CueO laccase
*CueO laccase

Revision as of 11:34, 16 February 2016

CotA laccase complex with glycerol, O2 and Cu+2 (orange), 1w6l

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3D structures of CotA laccase

Updated on 16-February-2016

See Blue copper oxidase CueO

References

  1. Hullo MF, Moszer I, Danchin A, Martin-Verstraete I. CotA of Bacillus subtilis is a copper-dependent laccase. J Bacteriol. 2001 Sep;183(18):5426-30. PMID:11514528
  2. Bento I, Martins LO, Gato Lopes G, Armenia Carrondo M, Lindley PF. Dioxygen reduction by multi-copper oxidases; a structural perspective. Dalton Trans. 2005 Nov 7;(21):3507-13. Epub 2005 Sep 27. PMID:16234932 doi:10.1039/b504806k
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