4xe5
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the Na,K-ATPase from bovine== | |
| - | + | <StructureSection load='4xe5' size='340' side='right' caption='[[4xe5]], [[Resolution|resolution]] 3.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xe5]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XE5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XE5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OBN:OUABAIN'>OBN</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BFD:ASPARTATE+BERYLLIUM+TRIFLUORIDE'>BFD</scene></td></tr> |
| - | [[Category: Gregersen, J | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sodium/potassium-exchanging_ATPase Sodium/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.9 3.6.3.9] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xe5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xe5 OCA], [http://pdbe.org/4xe5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xe5 RCSB], [http://www.ebi.ac.uk/pdbsum/4xe5 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AT1A1_BOVIN AT1A1_BOVIN]] This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients (By similarity). [[http://www.uniprot.org/uniprot/ATNG_BOVIN ATNG_BOVIN]] May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. [[http://www.uniprot.org/uniprot/G3MWR4_BOVIN G3MWR4_BOVIN]] This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.[RuleBase:RU362099] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Sodium/potassium-exchanging ATPase]] | ||
| + | [[Category: Fedosova, N U]] | ||
| + | [[Category: Gregersen, J L]] | ||
| + | [[Category: Mattle, D]] | ||
[[Category: Nissen, P]] | [[Category: Nissen, P]] | ||
| - | [[Category: Fedosova, N.U]] | ||
| - | [[Category: Mattle, D]] | ||
[[Category: Reinhard, L]] | [[Category: Reinhard, L]] | ||
| + | [[Category: Alpha-helical transmembrane protein]] | ||
| + | [[Category: Atp binding]] | ||
| + | [[Category: Atpase]] | ||
| + | [[Category: Beryllium trifluoride]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Multisubunit complex]] | ||
| + | [[Category: Plasma membrane]] | ||
| + | [[Category: Potassium ion transport]] | ||
| + | [[Category: Receptor for cardiotonic steroid]] | ||
| + | [[Category: Sodium binding]] | ||
| + | [[Category: Sodium ion transport]] | ||
Revision as of 03:45, 10 March 2016
Crystal structure of the Na,K-ATPase from bovine
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Categories: Bos taurus | Sodium/potassium-exchanging ATPase | Fedosova, N U | Gregersen, J L | Mattle, D | Nissen, P | Reinhard, L | Alpha-helical transmembrane protein | Atp binding | Atpase | Beryllium trifluoride | Hydrolase | Membrane protein | Multisubunit complex | Plasma membrane | Potassium ion transport | Receptor for cardiotonic steroid | Sodium binding | Sodium ion transport
