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4xki
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Human Fibroblast Growth Factor - 1 (FGF-1) mutant S116R== |
| - | + | <StructureSection load='4xki' size='340' side='right' caption='[[4xki]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xki]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XKI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2PE:NONAETHYLENE+GLYCOL'>2PE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xki OCA], [http://pdbe.org/4xki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xki RCSB], [http://www.ebi.ac.uk/pdbsum/4xki PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN]] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Xia, X]] | [[Category: Xia, X]] | ||
| + | [[Category: Fibroblast growth factor fgf-1 increased heparin binding affinity]] | ||
| + | [[Category: Growth factor]] | ||
Revision as of 17:13, 20 January 2016
Human Fibroblast Growth Factor - 1 (FGF-1) mutant S116R
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