5f4v

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'''Unreleased structure'''
 
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The entry 5f4v is ON HOLD until Paper Publication
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==Crystal structure of the human sperm Izumo1 residues 22-256==
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<StructureSection load='5f4v' size='340' side='right' caption='[[5f4v]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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Authors: Aydin, H., Sultana, A., Lee, J.E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5f4v]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F4V FirstGlance]. <br>
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Description: Crystal structure of a human glycoprotein 2
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f4e|5f4e]], [[5f4q|5f4q]], [[5f4t|5f4t]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f4v OCA], [http://pdbe.org/5f4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f4v RCSB], [http://www.ebi.ac.uk/pdbsum/5f4v PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/IZUM1_HUMAN IZUM1_HUMAN]] Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'.<ref>PMID:15759005</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Aydin, H]]
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[[Category: Lee, J E]]
[[Category: Sultana, A]]
[[Category: Sultana, A]]
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[[Category: Aydin, H]]
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[[Category: Adhesion]]
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[[Category: Lee, J.E]]
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[[Category: Cell adhesion]]
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[[Category: Cysteine-rich]]
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[[Category: Fusion]]
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[[Category: Glycoprotein]]
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[[Category: Membrane-bound]]

Revision as of 22:25, 20 June 2016

Crystal structure of the human sperm Izumo1 residues 22-256

5f4v, resolution 2.90Å

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