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5fdd

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m (Protected "5fdd" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==Endonuclease inhibitor 1 bound to influenza strain H1N1 polymerase acidic subunit N-terminal region at pH 7.0==
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<StructureSection load='5fdd' size='340' side='right' caption='[[5fdd]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
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The entry 5fdd is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5fdd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FDD FirstGlance]. <br>
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Authors: Fudo, S., Yamamoto, N., Nukaga, M., Odagiri, T., Tashiro, M., Hoshino, T.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4P8:5-(2-CHLOROBENZYL)-2-HYDROXY-3-NITROBENZALDEHYDE'>4P8</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zhz|4zhz]], [[5fde|5fde]], [[5fdg|5fdg]]</td></tr>
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Description: Phenolic acid derivative bound to influenza strain H1N1 polymerase subunit PA endonuclease
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdd OCA], [http://pdbe.org/5fdd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fdd RCSB], [http://www.ebi.ac.uk/pdbsum/5fdd PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Hoshino, T]]
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== Function ==
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[[Category: Tashiro, M]]
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[[http://www.uniprot.org/uniprot/PA_I34A1 PA_I34A1]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication.
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__TOC__
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</StructureSection>
[[Category: Fudo, S]]
[[Category: Fudo, S]]
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[[Category: Hoshino, T]]
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[[Category: Nukaga, M]]
[[Category: Odagiri, T]]
[[Category: Odagiri, T]]
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[[Category: Tashiro, M]]
[[Category: Yamamoto, N]]
[[Category: Yamamoto, N]]
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[[Category: Nukaga, M]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Hydrolase/inhibitor]]

Revision as of 19:41, 30 December 2015

Endonuclease inhibitor 1 bound to influenza strain H1N1 polymerase acidic subunit N-terminal region at pH 7.0

5fdd, resolution 2.51Å

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