1b7g

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1b7g.jpg|left|200px]]
[[Image:1b7g.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1b7g |SIZE=350|CAPTION= <scene name='initialview01'>1b7g</scene>, resolution 2.05&Aring;
+
The line below this paragraph, containing "STRUCTURE_1b7g", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </span>
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1b7g| PDB=1b7g | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b7g OCA], [http://www.ebi.ac.uk/pdbsum/1b7g PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1b7g RCSB]</span>
+
-
}}
+
'''GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE'''
'''GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE'''
Line 23: Line 20:
==Reference==
==Reference==
Crystal structure of the glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus., Isupov MN, Fleming TM, Dalby AR, Crowhurst GS, Bourne PC, Littlechild JA, J Mol Biol. 1999 Aug 20;291(3):651-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10448043 10448043]
Crystal structure of the glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus., Isupov MN, Fleming TM, Dalby AR, Crowhurst GS, Bourne PC, Littlechild JA, J Mol Biol. 1999 Aug 20;291(3):651-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10448043 10448043]
-
[[Category: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)]]
 
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Sulfolobus solfataricus]]
[[Category: Sulfolobus solfataricus]]
[[Category: Isupov, M N.]]
[[Category: Isupov, M N.]]
[[Category: Littlechild, J A.]]
[[Category: Littlechild, J A.]]
-
[[Category: archaea]]
+
[[Category: Archaea]]
-
[[Category: gapdh]]
+
[[Category: Gapdh]]
-
[[Category: hyperthermophile]]
+
[[Category: Hyperthermophile]]
-
[[Category: hyperthermophilic dehydrogenase]]
+
[[Category: Hyperthermophilic dehydrogenase]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 11:10:00 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:55:09 2008''
+

Revision as of 08:10, 2 May 2008

Template:STRUCTURE 1b7g

GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE


Overview

The enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from the archaea shows low sequence identity (16-20%) with its eubacterial and eukaryotic counterparts. The crystal structure of the apo GAPDH from Sulfolobus solfataricus has been determined by multiple isomorphous replacement at 2.05 A resolution. The enzyme has several differences in secondary structure when compared with eubacterial GAPDHs, with an overall increase in the number of alpha-helices. There is a relocation of the active-site residues within the catalytic domain of the enzyme. The thermostability of the S. solfataricus enzyme can be attributed to a combination of an ion pair cluster and an intrasubunit disulphide bond.

About this Structure

1B7G is a Single protein structure of sequence from Sulfolobus solfataricus. Full crystallographic information is available from OCA.

Reference

Crystal structure of the glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus., Isupov MN, Fleming TM, Dalby AR, Crowhurst GS, Bourne PC, Littlechild JA, J Mol Biol. 1999 Aug 20;291(3):651-60. PMID:10448043 Page seeded by OCA on Fri May 2 11:10:00 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools