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Diguanylate cyclase

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'''Diguanylate cyclase''' (DGC) catalyzes the conversion of GTP to cyclic di-GMP and diphosphate. <ref>PMID:17697992</ref> For more details see [[PleD catalysis]].
'''Diguanylate cyclase''' (DGC) catalyzes the conversion of GTP to cyclic di-GMP and diphosphate. <ref>PMID:17697992</ref> For more details see [[PleD catalysis]].
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== Disease ==
 
== Relevance ==
== Relevance ==
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DGC from ''Borrelia burgdorferi'' is involved in the transmission of spirochetes from ticks to mammals causing Lyme Disease.
== Structural highlights ==
== Structural highlights ==

Revision as of 10:39, 24 December 2015

Diguanylate cyclase GGDEF domain complex with cyclid di-GMP, glycerol and MES (PDB code 4urs).

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3D Structures of diguanylate cyclase

Updated on 24-December-2015

References

  1. ↑ Stock AM. Diguanylate cyclase activation: it takes two. Structure. 2007 Aug;15(8):887-8. PMID:17697992 doi:http://dx.doi.org/10.1016/j.str.2007.07.003

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