Deaminase
From Proteopedia
(Difference between revisions)
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**[[1r5t]] – yCDA - yeast <BR /> | **[[1r5t]] – yCDA - yeast <BR /> | ||
**[[2a8n]] – AtCDA – ''Agrobacterium tumefaciens'' <BR /> | **[[2a8n]] – AtCDA – ''Agrobacterium tumefaciens'' <BR /> | ||
| - | **[[2g84]] – | + | **[[2g84]] – NeCDA – ''Nitrosomonas europaea'' <BR /> |
**[[2d30]] – CDA – ''Bacillus anthracis'' <BR /> | **[[2d30]] – CDA – ''Bacillus anthracis'' <BR /> | ||
**[[3dmo]] – CDA – ''Burkholderia pseudomallei'' <BR /> | **[[3dmo]] – CDA – ''Burkholderia pseudomallei'' <BR /> | ||
**[[3ijf]] – MtCDA – ''Mycobacterium tuberculosis'' <BR /> | **[[3ijf]] – MtCDA – ''Mycobacterium tuberculosis'' <BR /> | ||
| + | **[[4wif]], [[4wig]] – MtCDA (mutant) <BR /> | ||
**[[3mpz]] – CDA – ''Mycobacterium smegmatis'' <BR /> | **[[3mpz]] – CDA – ''Mycobacterium smegmatis'' <BR /> | ||
**[[3r2n]] – CDA – ''Mycobacterium leprae'' <BR /> | **[[3r2n]] – CDA – ''Mycobacterium leprae'' <BR /> | ||
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**[[2i9u]] – GDA + guanine – ''Clostridium acetobutylicum'' <BR /> | **[[2i9u]] – GDA + guanine – ''Clostridium acetobutylicum'' <BR /> | ||
**[[2ood]] – GDA + guanine – ''Bradrhizobium japonicum'' <BR /> | **[[2ood]] – GDA + guanine – ''Bradrhizobium japonicum'' <BR /> | ||
| + | **[[4lc5]], [[4lcn]], [[4hrq]] – NeGDA + guanine derivative<BR /> | ||
| + | **[[4hrw]] – NeGDA (mutant) + guanine derivative<BR /> | ||
| + | **[[4lco]] – NeGDA + ameline<BR /> | ||
| + | **[[4lcp]] – NeGDA + diaminopurine<BR /> | ||
| + | **[[4ld2]] – NeGDA + cytidine<BR /> | ||
| + | **[[4ld4]] – NeGDA + cytosine<BR /> | ||
**[[2uz9]] – hGDA + xanthine <BR /> | **[[2uz9]] – hGDA + xanthine <BR /> | ||
**[[4aql]] – hGDA + valacyclovir <BR /> | **[[4aql]] – hGDA + valacyclovir <BR /> | ||
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**[[2bkx]] – BsGPD + fructose 6-phosphate<BR /> | **[[2bkx]] – BsGPD + fructose 6-phosphate<BR /> | ||
**[[4r7t]] – VcGPD <br /> | **[[4r7t]] – VcGPD <br /> | ||
| + | **[[5hj5]] – VcGPD + fructose 6-phosphate + glucose-6-phosphate<BR /> | ||
**[[1hor]] – EcGPD + deoxy-amino glucitol-phosphate<BR /> | **[[1hor]] – EcGPD + deoxy-amino glucitol-phosphate<BR /> | ||
**[[1hot]], [[1frz]], [[1fs5]], [[2wu1]] – EcGPD + N-acetyl-glucosamine-6-phosphate<BR /> | **[[1hot]], [[1frz]], [[1fs5]], [[2wu1]] – EcGPD + N-acetyl-glucosamine-6-phosphate<BR /> | ||
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**[[2hxd]] – MjDCD-DUT (mutant) + dUTP derivative<BR /> | **[[2hxd]] – MjDCD-DUT (mutant) + dUTP derivative<BR /> | ||
**[[1pkk]] – MjDCD-DUT + dCTP<BR /> | **[[1pkk]] – MjDCD-DUT + dCTP<BR /> | ||
| + | **[[4xjc]] – DCD-DUT + TTP – ''Bacillus halodurans''<BR /> | ||
| + | **[[4a6a]] – MtDCD-DUT (mutant) + TTP <BR /> | ||
*Porphobilinogen deaminase See [[Porphobilinogen Deaminase]] | *Porphobilinogen deaminase See [[Porphobilinogen Deaminase]] | ||
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**[[3ss7]], [[3ss9]] – EcDSD + PLP <BR /> | **[[3ss7]], [[3ss9]] – EcDSD + PLP <BR /> | ||
**[[3gwq]] – DSD - ''Burkholderia xenovorans''<BR /> | **[[3gwq]] – DSD - ''Burkholderia xenovorans''<BR /> | ||
| + | |||
| + | *L-amino acid deaminase | ||
| + | |||
| + | **[[5fjm]] – PmLSD – ''Proteus myxofaciens'' <BR /> | ||
| + | **[[5fjn]] – PmLSD + anthranilate <BR /> | ||
| + | |||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:23, 13 April 2017
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3D Structures of deaminase
Updated on 13-April-2017
References
- ↑ Bransteitter R, Pham P, Scharff MD, Goodman MF. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4102-7. Epub 2003 Mar 21. PMID:12651944 doi:http://dx.doi.org/10.1073/pnas.0730835100
- ↑ Egeblad L, Welin M, Flodin S, Graslund S, Wang L, Balzarini J, Eriksson S, Nordlund P. Pan-Pathway Based Interaction Profiling of FDA-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism. PLoS One. 2012;7(5):e37724. Epub 2012 May 25. PMID:22662200 doi:10.1371/journal.pone.0037724
- ↑ Negroni L, Samson M, Guigonis JM, Rossi B, Pierrefite-Carle V, Baudoin C. Treatment of colon cancer cells using the cytosine deaminase/5-fluorocytosine suicide system induces apoptosis, modulation of the proteome, and Hsp90beta phosphorylation. Mol Cancer Ther. 2007 Oct;6(10):2747-56. PMID:17938268 doi:http://dx.doi.org/10.1158/1535-7163.MCT-07-0040
- ↑ Ireton GC, Black ME, Stoddard BL. The 1.14 A crystal structure of yeast cytosine deaminase: evolution of nucleotide salvage enzymes and implications for genetic chemotherapy. Structure. 2003 Aug;11(8):961-72. PMID:12906827
