Dehydroquinase
From Proteopedia
(Difference between revisions)
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**[[4clm]], [[4cno]], [[4cnp]] – StDHQD + inhibitor<br /> | **[[4clm]], [[4cno]], [[4cnp]] – StDHQD + inhibitor<br /> | ||
**[[4h3d]] – CdDHQD + comenic acid <br /> | **[[4h3d]] – CdDHQD + comenic acid <br /> | ||
| + | **[[4uio]] – DHQD + dehydroquinic acid derivative – ''Salmonella enterica''<br /> | ||
*DHQD-II | *DHQD-II | ||
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**[[1d0i]], [[1gu0]] – ScDHQD – ''Streptomyces coelicolor'' <br /> | **[[1d0i]], [[1gu0]] – ScDHQD – ''Streptomyces coelicolor'' <br /> | ||
**[[2dhq]], [[1h05]] – MtDHQD – ''Mycobacterium tuberculosis'' <br /> | **[[2dhq]], [[1h05]] – MtDHQD – ''Mycobacterium tuberculosis'' <br /> | ||
| + | **[[4ckw]], [[4ckx]], [[4ckz]] – MtDHQD (mutant) <br /> | ||
**[[1gqo]] – DHQD – ''Bacillus subtilis'' <br /> | **[[1gqo]] – DHQD – ''Bacillus subtilis'' <br /> | ||
**[[1uqr]] – DHQD – ''Actinobacillus pleuropneumoniae''<br /> | **[[1uqr]] – DHQD – ''Actinobacillus pleuropneumoniae''<br /> | ||
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**[[3u80]] – DHQD – ''Bifidobacterium longum'' <br /> | **[[3u80]] – DHQD – ''Bifidobacterium longum'' <br /> | ||
**[[4l8l]] – DHQD – ''Pseudomonas aeruginosa'' <br /> | **[[4l8l]] – DHQD – ''Pseudomonas aeruginosa'' <br /> | ||
| - | **[[4rc9]], [[4rhc]] – DHQD – ''Acinetobacter baumannii''<br /> | + | **[[4rc9]], [[4rhc]], [[4zc1]], [[5b6p]], [[5wrf]], [[5x47]] – DHQD – ''Acinetobacter baumannii''<br /> |
*DHQD-II complexes | *DHQD-II complexes | ||
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**[[3n8k]] – MtDHQD + citrazinic acid<br /> | **[[3n8k]] – MtDHQD + citrazinic acid<br /> | ||
**[[2xb8]], [[3n76]], [[3n7a]], [[3n86]], [[3n87]], [[3n8n]], [[2y71]], [[2y76]], [[2y77]], [[4b6o]], [[4b6p]], [[4b6q]], [[4civ]], [[4cix]], [[4ciw]], [[4ciy]], [[4ki7]], [[4kij]], [[4kiu]], [[4kiw]] – MtDHQD + inhibitor<br /> | **[[2xb8]], [[3n76]], [[3n7a]], [[3n86]], [[3n87]], [[3n8n]], [[2y71]], [[2y76]], [[2y77]], [[4b6o]], [[4b6p]], [[4b6q]], [[4civ]], [[4cix]], [[4ciw]], [[4ciy]], [[4ki7]], [[4kij]], [[4kiu]], [[4kiw]] – MtDHQD + inhibitor<br /> | ||
| + | **[[4cky]], [[4cl0]] – MtDHQD + dehydroquinic acid derivative<br /> | ||
| + | **[[4v0s]] – MtDHQD (mutant) + dehydroquinic acid derivative<br /> | ||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:55, 13 April 2017
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3D structures of dehydroquinase
Updated on 13-April-2017
References
- ↑ Herrmann KM. The Shikimate Pathway: Early Steps in the Biosynthesis of Aromatic Compounds. Plant Cell. 1995 Jul;7(7):907-919. PMID:12242393 doi:http://dx.doi.org/10.1105/tpc.7.7.907
- ↑ Dias MV, Snee WC, Bromfield KM, Payne R, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem J. 2011 Mar 17. PMID:21410435 doi:10.1042/BJ20110002
- ↑ Light SH, Antanasijevic A, Krishna SN, Caffrey M, Anderson WF, Lavie A. Crystal structures of type I dehydroquinate dehydratase in complex with quinate and shikimate suggest a novel mechanism of Schiff base formation. Biochemistry. 2014 Feb 11;53(5):872-80. doi: 10.1021/bi4015506. Epub 2014 Jan 31. PMID:24437575 doi:http://dx.doi.org/10.1021/bi4015506
