5es6

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'''Unreleased structure'''
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==Crystal structure of the first two domains of the initiation module of LgrA==
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<StructureSection load='5es6' size='340' side='right' caption='[[5es6]], [[Resolution|resolution]] 2.46&Aring;' scene=''>
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The entry 5es6 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5es6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ES6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ES6 FirstGlance]. <br>
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Authors: Reimer, J.M., Aloise, M.N., Schmeing, T.M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5es5|5es5]], [[5es7|5es7]], [[5es8|5es8]], [[5es9|5es9]]</td></tr>
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Description:
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5es6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5es6 OCA], [http://pdbe.org/5es6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5es6 RCSB], [http://www.ebi.ac.uk/pdbsum/5es6 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Aloise, M.N]]
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== Function ==
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[[Category: Reimer, J.M]]
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[[http://www.uniprot.org/uniprot/LGRA_BREPA LGRA_BREPA]] Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide.
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[[Category: Schmeing, T.M]]
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__TOC__
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</StructureSection>
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[[Category: Aloise, M N]]
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[[Category: Reimer, J M]]
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[[Category: Schmeing, T M]]
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[[Category: Adenylation domain]]
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[[Category: Formylation domain]]
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[[Category: Initiation module]]
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[[Category: Ligase]]
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[[Category: Nrp]]

Revision as of 17:24, 20 January 2016

Crystal structure of the first two domains of the initiation module of LgrA

5es6, resolution 2.46Å

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