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5es8
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of the initiation module of LgrA in the thiolation state== |
| - | + | <StructureSection load='5es8' size='340' side='right' caption='[[5es8]], [[Resolution|resolution]] 2.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5es8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ES8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ES8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5S4:[(3~{R})-4-[[3-[2-[[(2~{S})-2-AZANYL-3-METHYL-BUTANOYL]AMINO]ETHYLAMINO]-3-OXIDANYLIDENE-PROPYL]AMINO]-2,2-DIMETHYL-3-OXIDANYL-4-OXIDANYLIDENE-BUTYL]+DIHYDROGEN+PHOSPHATE'>5S4</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5es5|5es5]], [[5es6|5es6]], [[5es7|5es7]], [[5es9|5es9]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5es8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5es8 OCA], [http://pdbe.org/5es8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5es8 RCSB], [http://www.ebi.ac.uk/pdbsum/5es8 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[Category: Aloise, M | + | == Function == |
| - | [[Category: Reimer, J | + | [[http://www.uniprot.org/uniprot/LGRA_BREPA LGRA_BREPA]] Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide. |
| - | [[Category: Schmeing, T | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Aloise, M N]] | ||
| + | [[Category: Reimer, J M]] | ||
| + | [[Category: Schmeing, T M]] | ||
| + | [[Category: Adenylation domain]] | ||
| + | [[Category: Formylation domain]] | ||
| + | [[Category: Ligase]] | ||
| + | [[Category: Nrp]] | ||
| + | [[Category: Peptidyl carrier protein]] | ||
Revision as of 17:24, 20 January 2016
Crystal structure of the initiation module of LgrA in the thiolation state
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