5fr3
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==X-ray crystal structure of aggregation-resistant protective antigen of Bacillus anthracis (mutant S559L T576E)== |
| - | + | <StructureSection load='5fr3' size='340' side='right' caption='[[5fr3]], [[Resolution|resolution]] 1.94Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5fr3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FR3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FR3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fr3 OCA], [http://pdbe.org/5fr3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fr3 RCSB], [http://www.ebi.ac.uk/pdbsum/5fr3 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN]] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Beerten, J]] | [[Category: Beerten, J]] | ||
| - | [[Category: Vandurme, J]] | ||
| - | [[Category: Rousseau, F]] | ||
[[Category: Brams, M]] | [[Category: Brams, M]] | ||
| - | [[Category: | + | [[Category: DeBaets, G]] |
| - | [[Category: | + | [[Category: DeSmet, F]] |
[[Category: Gallardo, R]] | [[Category: Gallardo, R]] | ||
| - | [[Category: Debaets, G]] | ||
| - | [[Category: Ramakers, M]] | ||
| - | [[Category: Langenberg, T]] | ||
[[Category: Ganesan, A]] | [[Category: Ganesan, A]] | ||
| + | [[Category: Langenberg, T]] | ||
| + | [[Category: Ramakers, M]] | ||
| + | [[Category: Rousseau, F]] | ||
[[Category: Schymkowitz, J]] | [[Category: Schymkowitz, J]] | ||
| - | [[Category: | + | [[Category: Siekierska, A]] |
| - | + | ||
[[Category: Ulens, C]] | [[Category: Ulens, C]] | ||
| + | [[Category: Wilkinson, H]] | ||
| + | [[Category: VanDurme, J]] | ||
| + | [[Category: VanderKant, R]] | ||
| + | [[Category: Anthrax protective antigen]] | ||
| + | [[Category: Toxin]] | ||
Revision as of 02:37, 28 January 2016
X-ray crystal structure of aggregation-resistant protective antigen of Bacillus anthracis (mutant S559L T576E)
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