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DNA damage-binding protein

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== Disease ==
== Disease ==
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Defective activity of DDB2 causes the repair defects in patients with XPE - an autosomal disorder characterized by early onset of cancer and photosensitivity. <ref>PMID:18593899</ref>
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Defective activity of DDB2 causes the repair defects in patients with XPE - an autosomal disorder characterized by early onset of cancer and photosensitivity.
</StructureSection>
</StructureSection>
== 3D Structures of DNA damage-binding protein ==
== 3D Structures of DNA damage-binding protein ==

Revision as of 12:51, 31 December 2015

Human DDB1 (grey) and DDB2 (green) complex with DNA, TMP and tetraethylene glycol (PDB code 3ei1).

Drag the structure with the mouse to rotate

3D Structures of DNA damage-binding protein

Updated on 31-December-2015

References

  1. Guerrero-Santoro J, Kapetanaki MG, Hsieh CL, Gorbachinsky I, Levine AS, Rapic-Otrin V. The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A. Cancer Res. 2008 Jul 1;68(13):5014-22. PMID:18593899 doi:68/13/5014

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