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DNA ligase

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**[[4hto]] - hLigD IV DNA-binding domain<br />
**[[4hto]] - hLigD IV DNA-binding domain<br />
**[[4htp]] - hLigD IV DNA-binding domain + artemis protein peptide<br />
**[[4htp]] - hLigD IV DNA-binding domain + artemis protein peptide<br />
-
**[[3w1b]], [[3w1g]] - hLigD IV + artemis protein peptide<br />
+
**[[3w1b]], [[3w1g]] - hLigD IV adenylation and DNA-binding domains + artemis protein peptide<br />
}}
}}

Revision as of 13:12, 31 December 2015

ATP-dependent DNA ligase complexed with ATP 2hix

Drag the structure with the mouse to rotate

3D Structures of DNA ligase

Updated on 31-December-2015

REFERENCES

Elevated expression of DNA ligase I in human cancers., Sun DY, Urrabaz R, Nguyen M, Marty J, Stringer S, Cruz E, Medina-Gundrum L, Weitman S., Clinical Cancer Research. 2001; 7(12):4143-4148.
Replication failure, genome instability, and increased cancer susceptibility in mice with a point mutation in the DNA ligase I gene., Harrison C, Ketchen AM, Redhead NJ, O'Sullivan MJ, Melton DW., Cancer Research. 2002; 62(14):4065-4074.

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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