Interleukin
From Proteopedia
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* '''IL-7''' is a cytokine important for B and T cells development.<br /> | * '''IL-7''' is a cytokine important for B and T cells development.<br /> | ||
* '''IL-8''' induces chemotaxis and phagocytosis.<br /> | * '''IL-8''' induces chemotaxis and phagocytosis.<br /> | ||
| - | * '''IL-10''' see [[Interleukin-10]].<br /> | + | * '''IL-10''' see [[Interleukin-10]] and [[Inflammation & Rheumatoid Arthritis]].<br /> |
* '''IL-11''' involved in the stimulation of megakaryocyte maturation.<br /> | * '''IL-11''' involved in the stimulation of megakaryocyte maturation.<br /> | ||
* ''' IL-12''' induces the differentiation of naive helper T cells (Th0) to Th1 cells.<br /> | * ''' IL-12''' induces the differentiation of naive helper T cells (Th0) to Th1 cells.<br /> | ||
Revision as of 10:59, 10 February 2016
Template:STRUCTURE 2nvh
Interleukin (IL) is a cytokine which functions in the immune system. IL deficiency results in autoimmune disease. IL families are denoted by numbers.
- IL-1 is a group of 11 cytokines which regulate immune and inflammatory response. See Interleukin-1 beta.
- IL-2 is a cytokine made by leukocytes. It is used in cancer therapy to boost the immune system.
- IL-3 improves the body's natural response to disease by stimulating the differentiation of multipotent hematopoietic stem cells into myeloid or lymphoid progenitor cells.
- IL-4 induces the differentiation of naive helper T cells (Th0) to Th2 cells.
- IL-5 stimulates B cell growth and increases immunoglobulin secretion.
- IL-6 is both a pro-inflammatory cytokine and anti-inflammatory myokine.
- IL-7 is a cytokine important for B and T cells development.
- IL-8 induces chemotaxis and phagocytosis.
- IL-10 see Interleukin-10 and Inflammation & Rheumatoid Arthritis.
- IL-11 involved in the stimulation of megakaryocyte maturation.
- IL-12 induces the differentiation of naive helper T cells (Th0) to Th1 cells.
- IL-13 induces the differentiation of naive helper T cells (Th0) to Th2 cells.
- IL-15 see Interleukin-15.
- IL-16 acts as chemoattractant, modulator of T cell activity and inhibitor of HIV replication.
- IL-17 recruits monocytes and neutrophils to the site of inflammation.
- IL-18 induces cell-mediated immunity following infection by microbial lipopolysaccharides.
- IL-19 induces activation of the signal transducer and activator of STAT3.
- IL-21 has potent effect on natural killer cells.
- IL-22 stimulates inflammatory responses like S100 and defensin.
- IL-23 induces activation of the signal transducer and activator of STAT4.
- IL-28 has a role in the immune defense against viruses.
- IL-29 similar to IL-28.
- IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines.
- IL-34 increases growth or survival of monocytes.
- IL-36 acts on naïve CD4+ T cells.
3D structures of interleukin
Updated on 10-February-2016
