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2mxc
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of the full length sorting nexin 3== | |
| - | + | <StructureSection load='2mxc' size='340' side='right' caption='[[2mxc]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2mxc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MXC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mxc OCA], [http://pdbe.org/2mxc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mxc RCSB], [http://www.ebi.ac.uk/pdbsum/2mxc PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: Rajesh, S | + | [[http://www.uniprot.org/uniprot/SNX3_HUMAN SNX3_HUMAN]] MMEP syndrome. The gene represented in this entry may be involved in disease pathogenesis. A chromosomal aberration involving SNX3 has been found in patients with syndromic microphthalmia. Translocation t(6;13)(q21;q12). |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/SNX3_HUMAN SNX3_HUMAN]] Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Plays a role in protein transport between cellular compartments. Promotes stability and cell surface expression of epithelial sodium channel (ENAC) subunits SCNN1A and SCNN1G (By similarity). Not involved in EGFR degradation.<ref>PMID:11433298</ref> <ref>PMID:18767904</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Gruenberg, J J.G]] | ||
| + | [[Category: Kaur, J J.K]] | ||
| + | [[Category: Lenoir, M M.L]] | ||
| + | [[Category: Overduin, M M.O]] | ||
| + | [[Category: Rajesh, S S.R]] | ||
| + | [[Category: Endosome]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Pi3p]] | ||
| + | [[Category: Protein transport]] | ||
| + | [[Category: Snx3]] | ||
Revision as of 19:30, 13 May 2016
Solution structure of the full length sorting nexin 3
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