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5ea9
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Trypanosoma cruzi Dihydroorotate Dehydrogenase in Complex with Neq0130== | |
| - | + | <StructureSection load='5ea9' size='340' side='right' caption='[[5ea9]], [[Resolution|resolution]] 1.71Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ea9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EA9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5LM:5-[(E)-3-THIOPHEN-2-YLPROP-2-ENYLIDENE]-1,3-DIAZINANE-2,4,6-TRIONE'>5LM</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5e93|5e93]]</td></tr> |
| - | [[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ea9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ea9 OCA], [http://pdbe.org/5ea9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ea9 RCSB], [http://www.ebi.ac.uk/pdbsum/5ea9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ea9 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cheleski, J]] | ||
[[Category: Harada, S]] | [[Category: Harada, S]] | ||
| - | [[Category: | + | [[Category: Inaoka, D K]] |
[[Category: Kita, K]] | [[Category: Kita, K]] | ||
| - | [[Category: Montanari, C | + | [[Category: Montanari, C A]] |
| - | [[Category: Rocha, J | + | [[Category: Rocha, J R]] |
| + | [[Category: Shiba, T]] | ||
| + | [[Category: Covalent inhibitor]] | ||
| + | [[Category: Dihydroorotate dehydrogenase]] | ||
| + | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
| + | [[Category: T. cruzi]] | ||
Revision as of 00:56, 20 October 2016
Crystal Structure of Trypanosoma cruzi Dihydroorotate Dehydrogenase in Complex with Neq0130
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