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Avidin

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Avidin is one of the [[CBI Molecules]] being studied in the [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].
Avidin is one of the [[CBI Molecules]] being studied in the [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].
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<scene name='41/410356/Cv/5'>Avidin is a tetrameric protein</scene> what in different words means that if we could, we would see a protein with four regions that look identical one to the other. However, to isolate the four regions as a whole in order to show the protein three dimensional structure has been quite diffucult so far and we just can see the three dimensional structure for <scene name='41/410356/Cv/7'>two of those four units</scene>. <ref group="xtra">PMID:8506353</ref><ref group="xtra">PMID:8344421</ref>
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<scene name='41/410356/Cv/5'>Avidin is a tetrameric protein</scene> what in different words means that if we could, we would see a protein with four regions that look identical one to the other. However, to isolate the four regions as a whole in order to show the protein three dimensional structure has been quite diffucult so far and we just can see the three dimensional structure for <scene name='41/410356/Cv/11'>two of those four units</scene>. <ref group="xtra">PMID:8506353</ref><ref group="xtra">PMID:8344421</ref>
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Revision as of 12:56, 12 January 2016

The avidin tetramer complex with biotin (PDB code 2avi)

Drag the structure with the mouse to rotate

3D structures of Avidin

Updated on 12-January-2016


Reference

  • Livnah O, Bayer EA, Wilchek M, Sussman JL. Three-dimensional structures of avidin and the avidin-biotin complex. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5076-80. PMID:8506353
  • Livnah O, Bayer EA, Wilchek M, Sussman JL. The structure of the complex between avidin and the dye, 2-(4'-hydroxyazobenzene) benzoic acid (HABA). FEBS Lett. 1993 Aug 9;328(1-2):165-8. PMID:8344421
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