This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2na8
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Transmembrane Structure of the Cytokine Receptor Common Subunit beta== | |
| - | + | <StructureSection load='2na8' size='340' side='right' caption='[[2na8]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2na8]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NA8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2na8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2na8 OCA], [http://pdbe.org/2na8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2na8 RCSB], [http://www.ebi.ac.uk/pdbsum/2na8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2na8 ProSAT]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[ | + | == Disease == |
| + | [[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] Defects in CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5) [MIM:[http://omim.org/entry/614370 614370]]. SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.<ref>PMID:21075760</ref> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: An, W]] | [[Category: An, W]] | ||
| - | [[Category: | + | [[Category: Ginsberg, M H]] |
[[Category: Schmidt, T]] | [[Category: Schmidt, T]] | ||
| + | [[Category: Situ, A J]] | ||
| + | [[Category: Ulmer, T S]] | ||
[[Category: Ye, F]] | [[Category: Ye, F]] | ||
| - | [[Category: | + | [[Category: Membrane protein]] |
| + | [[Category: Transmembrane helix]] | ||
Revision as of 17:54, 13 July 2016
Transmembrane Structure of the Cytokine Receptor Common Subunit beta
| |||||||||||
