5es9

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'''Unreleased structure'''
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==Crystal structure of the LgrA initiation module in the formylation state==
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<StructureSection load='5es9' size='340' side='right' caption='[[5es9]], [[Resolution|resolution]] 3.77&Aring;' scene=''>
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The entry 5es9 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5es9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ES9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ES9 FirstGlance]. <br>
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Authors: Reimer, J.M., Aloise, M.N., Schmeing, T.M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNS:4-PHOSPHOPANTETHEINE'>PNS</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5es5|5es5]], [[5es6|5es6]], [[5es7|5es7]], [[5es8|5es8]]</td></tr>
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Description:
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5es9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5es9 OCA], [http://pdbe.org/5es9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5es9 RCSB], [http://www.ebi.ac.uk/pdbsum/5es9 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Aloise, M.N]]
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== Function ==
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[[Category: Reimer, J.M]]
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[[http://www.uniprot.org/uniprot/LGRA_BREPA LGRA_BREPA]] Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide.
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[[Category: Schmeing, T.M]]
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__TOC__
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</StructureSection>
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[[Category: Aloise, M N]]
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[[Category: Reimer, J M]]
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[[Category: Schmeing, T M]]
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[[Category: Adenylation domain]]
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[[Category: Formylation domain]]
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[[Category: Initiation module]]
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[[Category: Ligase]]
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[[Category: Nrp]]
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[[Category: Peptidyl carrier protein]]

Revision as of 17:24, 20 January 2016

Crystal structure of the LgrA initiation module in the formylation state

5es9, resolution 3.77Å

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