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4x5f

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==ecDHFR complexed with folate and NADP+ at 0.1 MPa==
==ecDHFR complexed with folate and NADP+ at 0.1 MPa==
<StructureSection load='4x5f' size='340' side='right' caption='[[4x5f]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='4x5f' size='340' side='right' caption='[[4x5f]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4x5f]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X5F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4x5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X5F FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x5g|4x5g]], [[4x5h|4x5h]], [[4x5i|4x5i]], [[4x5j|4x5j]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x5g|4x5g]], [[4x5h|4x5h]], [[4x5i|4x5i]], [[4x5j|4x5j]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folA, tmrA, b0048, JW0047 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x5f OCA], [http://pdbe.org/4x5f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x5f RCSB], [http://www.ebi.ac.uk/pdbsum/4x5f PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x5f OCA], [http://pdbe.org/4x5f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x5f RCSB], [http://www.ebi.ac.uk/pdbsum/4x5f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x5f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</StructureSection>
</StructureSection>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
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[[Category: Ecoli]]
[[Category: Nagae, T]]
[[Category: Nagae, T]]
[[Category: Watanabe, N]]
[[Category: Watanabe, N]]
[[Category: Yamada, H]]
[[Category: Yamada, H]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 12:14, 6 November 2017

ecDHFR complexed with folate and NADP+ at 0.1 MPa

4x5f, resolution 1.70Å

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