Ceruloplasmin

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CP mutation causes the autosomal recessive disorder - Aceruloplasminemia which results in accumulation of iron in the brain.
CP mutation causes the autosomal recessive disorder - Aceruloplasminemia which results in accumulation of iron in the brain.
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== Structural highlights ==
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<scene name='46/467272/Cv/5'>Cu-O-Cu coordination site</scene>.
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</StructureSection>
</StructureSection>

Revision as of 10:57, 18 January 2016

Glycosylated human ceruloplasmin complex with Cu+2 ions (orange) and O atoms (red) (PDB entry 1kcw)

Drag the structure with the mouse to rotate

3D structures of ceruloplasmin

Updated on 18-January-2016

1kcw, 2j5w, 4enz – hCP - human
4ejx – hCP + myeloperoxidase

References

  1. Hellman NE, Gitlin JD. Ceruloplasmin metabolism and function. Annu Rev Nutr. 2002;22:439-58. Epub 2002 Apr 4. PMID:12055353 doi:http://dx.doi.org/10.1146/annurev.nutr.22.012502.114457

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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