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Epoxide hydrolase
From Proteopedia
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<StructureSection load='5alf' size='340' side='right' caption='Human soluble epoxide hydrolase complex with imidazole derivative inhibitor (PDB code [[5alf]])' scene=''> | <StructureSection load='5alf' size='340' side='right' caption='Human soluble epoxide hydrolase complex with imidazole derivative inhibitor (PDB code [[5alf]])' scene=''> | ||
| - | '''Epoxide hydrolase''' (EH) converts epoxides to trans-dihydrodiols which are excreted from the body. Thus, EH acts as a detoxification agent. Epoxides are formed from degradation of aromatic compounds.<br /> '''Bifunctional EH 2''' or '''soluble EH''' (SEH) is a bifunctional enzyme with the C-terminal domain having EH activity and the N-terminal domain having lipid phosphatase activity.<br /> '''Limonene-1,2-epoxide hydrolase''' catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. | ||
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== Function == | == Function == | ||
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| + | '''Epoxide hydrolase''' (EH) converts epoxides to trans-dihydrodiols which are excreted from the body. Thus, EH acts as a detoxification agent. Epoxides are formed from degradation of aromatic compounds.<br /> '''Bifunctional EH 2''' or '''soluble EH''' (SEH) is a bifunctional enzyme with the C-terminal domain having EH activity and the N-terminal domain having lipid phosphatase activity.<br /> '''Limonene-1,2-epoxide hydrolase''' catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. | ||
== Disease == | == Disease == | ||
Revision as of 20:12, 19 January 2016
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3D Structures of epoxide hydrolase
Updated on 19-January-2016
