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Epoxide hydrolase

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== Disease ==
== Disease ==
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Inhibitors of ''Mycobacterium tuberculosis'' EH such as urea derivatives, are used as anti-tuberculosis drugs. The valpromide inhibitor of EH is used as anti-epileptic drug.
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Inhibitors of ''Mycobacterium tuberculosis'' EH such as urea derivatives, are used as anti-tuberculosis drugs. The valpromide inhibitor of EH is used as anti-epileptic drug. Soluble EH plays a role in several diseases including cardiovascular ones and is a drug target for their therapy <ref>PMID:19794443</ref>.
== Relevance ==
== Relevance ==

Revision as of 21:10, 19 January 2016

Human soluble epoxide hydrolase complex with imidazole derivative inhibitor (PDB code 5alf)

Drag the structure with the mouse to rotate

3D Structures of epoxide hydrolase

Updated on 19-January-2016

References

  1. Imig JD, Hammock BD. Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases. Nat Rev Drug Discov. 2009 Oct;8(10):794-805. doi: 10.1038/nrd2875. PMID:19794443 doi:http://dx.doi.org/10.1038/nrd2875

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