5ft8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a Cysteine Desulfurase-Sulfur Acceptor Complex from Escherichia coli at 2.50 Angstroem resolution== | |
| - | + | <StructureSection load='5ft8' size='340' side='right' caption='[[5ft8]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ft8]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FT8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FT8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ft4|5ft4]], [[5ft5|5ft5]], [[5ft6|5ft6]], [[5ft7|5ft7]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ft8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ft8 OCA], [http://pdbe.org/5ft8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ft8 RCSB], [http://www.ebi.ac.uk/pdbsum/5ft8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ft8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CSDA_ECOLI CSDA_ECOLI]] Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. L-cysteine sulfinic acid is the best substrate. Functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.<ref>PMID:10829016</ref> [[http://www.uniprot.org/uniprot/CSDE_ECOLI CSDE_ECOLI]] Stimulates the cysteine desulfurase activity of CsdA. Contains a cysteine residue (Cys-61) that acts to accept sulfur liberated via the desulfurase activity of CsdA. May be able to transfer sulfur to TcdA/CsdL. Seems to support the function of TcdA in the generation of cyclic threonylcarbamoyladenosine at position 37 (ct(6)A37) in tRNAs that read codons beginning with adenine. Does not appear to participate in Fe/S biogenesis.<ref>PMID:15901727</ref> <ref>PMID:20054882</ref> <ref>PMID:23242255</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Aranda, J]] | ||
| + | [[Category: Arda, A]] | ||
| + | [[Category: Bruix, M]] | ||
[[Category: Campos-Oliva, R]] | [[Category: Campos-Oliva, R]] | ||
| - | [[Category: Fernandez, F.J]] | ||
| - | [[Category: Round, A]] | ||
[[Category: Coll, M]] | [[Category: Coll, M]] | ||
| - | [[Category: | + | [[Category: Fernandez, F J]] |
| - | [[Category: | + | [[Category: Garces, F]] |
| + | [[Category: Jimenez-Barbero, J]] | ||
[[Category: Lopez-Estepa, M]] | [[Category: Lopez-Estepa, M]] | ||
| - | [[Category: Bruix, M]] | ||
[[Category: Penya-Soler, E]] | [[Category: Penya-Soler, E]] | ||
| - | [[Category: | + | [[Category: Round, A]] |
| - | [[Category: | + | [[Category: Tunon, I]] |
| - | [[Category: | + | [[Category: Vega, M C]] |
| - | [[Category: | + | [[Category: L-cysteine desulfurase]] |
| + | [[Category: Sulfur acceptor]] | ||
| + | [[Category: Sulfur trafficking]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transpersulfuration]] | ||
Revision as of 10:51, 10 December 2016
Structure of a Cysteine Desulfurase-Sulfur Acceptor Complex from Escherichia coli at 2.50 Angstroem resolution
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