Estrogen-related receptor

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== Relevance ==
== Relevance ==
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ERR plays a role in energy homeostasis and cancer<ref>PMID:16515477</ref>.
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ERR plays a role in energy homeostasis and cancer<ref>PMID:16515477</ref>. ERRα and ERRγ are overexpressed in breast cancer and can serve as prognostic markers or therapeutic targets.
</StructureSection>
</StructureSection>

Revision as of 15:15, 20 January 2016

Human estrogen-related receptor γ ligand-binding domain (cyan, grey, green, yellow, pink, purple) complex with nuclear receptor corepressor 2 peptide (dark red, orange) and 4-hydroxytamoxifen (PDB code 2gpv)

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3D structures of estrogen-related receptor

Updated on 20-January-2016

References

  1. ↑ Ariazi EA, Jordan VC. Estrogen-related receptors as emerging targets in cancer and metabolic disorders. Curr Top Med Chem. 2006;6(3):203-15. PMID:16515477

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Wayne Decatur

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