5hnm
From Proteopedia
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| - | ''' | + | ==Crystal structure of vancomycin resistance D,D-pentapeptidase VanY E175A mutant from VanB-type resistance cassette in complex with Zn(II)== |
| - | + | <StructureSection load='5hnm' size='340' side='right' caption='[[5hnm]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5hnm]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HNM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HNM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hnm OCA], [http://pdbe.org/5hnm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hnm RCSB], [http://www.ebi.ac.uk/pdbsum/5hnm PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/VANY_ENTFA VANY_ENTFA]] Vancomycin-inducible, penicillin-resistant, DD-carboxypeptidase that hydrolyzes depsipeptide- and D-alanyl-D-alanine-containing peptidoglycan precursors. Insensitive to beta-lactams. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Serine-type D-Ala-D-Ala carboxypeptidase]] | ||
| + | [[Category: Anderson, W F]] | ||
| + | [[Category: Structural genomic]] | ||
[[Category: Chun, J]] | [[Category: Chun, J]] | ||
| + | [[Category: Courvalin, P]] | ||
| + | [[Category: Evdokimova, E]] | ||
| + | [[Category: Leo, R Di]] | ||
[[Category: Savchenko, A]] | [[Category: Savchenko, A]] | ||
| + | [[Category: Stogios, P J]] | ||
[[Category: Yim, V]] | [[Category: Yim, V]] | ||
| - | [[Category: | + | [[Category: Alpha+beta protein]] |
| - | [[Category: | + | [[Category: Antibiotic resistance]] |
| - | [[Category: | + | [[Category: Csgid]] |
| - | [[Category: | + | [[Category: Hedgehog/dd-peptidase fold]] |
| - | [[Category: | + | [[Category: Hydrolase]] |
| + | [[Category: Merops m15b subfamily]] | ||
| + | [[Category: Metallopeptidase]] | ||
| + | [[Category: National institute of allergy and infectious disease]] | ||
| + | [[Category: Niaid]] | ||
| + | [[Category: Vancomycin resistance]] | ||
| + | [[Category: Zn2+-dependent]] | ||
Revision as of 17:29, 10 February 2016
Crystal structure of vancomycin resistance D,D-pentapeptidase VanY E175A mutant from VanB-type resistance cassette in complex with Zn(II)
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Categories: Serine-type D-Ala-D-Ala carboxypeptidase | Anderson, W F | Structural genomic | Chun, J | Courvalin, P | Evdokimova, E | Leo, R Di | Savchenko, A | Stogios, P J | Yim, V | Alpha+beta protein | Antibiotic resistance | Csgid | Hedgehog/dd-peptidase fold | Hydrolase | Merops m15b subfamily | Metallopeptidase | National institute of allergy and infectious disease | Niaid | Vancomycin resistance | Zn2+-dependent
