Lysin

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The structure of lysin, refined at 1.9 angstroms resolution, reveals an alpha-helical, amphipathic molecule<scene name='60/607850/Alpha_helixes/1'>To see alpha helixes press here</scene>. you can see the alpha helixes in pink. <scene name='60/607850/Surface/1'>the surface of the protein</scene> exhibits three features: two tracks of basic residues that span the length of the molecule, a solvent-exposed cluster of <scene name='60/607850/Aromatic_and_aliphatic/1'>aromatic and aliphatic amino acids</scene>,(in green) and an extended amino-terminal hypervariable domain that is species-specific. The structure suggests possible mechanisms of action<ref>PMID:8266073</ref>.
The structure of lysin, refined at 1.9 angstroms resolution, reveals an alpha-helical, amphipathic molecule<scene name='60/607850/Alpha_helixes/1'>To see alpha helixes press here</scene>. you can see the alpha helixes in pink. <scene name='60/607850/Surface/1'>the surface of the protein</scene> exhibits three features: two tracks of basic residues that span the length of the molecule, a solvent-exposed cluster of <scene name='60/607850/Aromatic_and_aliphatic/1'>aromatic and aliphatic amino acids</scene>,(in green) and an extended amino-terminal hypervariable domain that is species-specific. The structure suggests possible mechanisms of action<ref>PMID:8266073</ref>.
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== 3D structure of lysin ==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[1lis]], [[1lyn]], [[2lis]], [[2lyn]], [[3lyn]] – Lys - abalone<br />
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[[1nkl]] – NK-Lys – pig – NMR<br />
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[[4cvd]] – Lys – bacteriophage CP-7<br />
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[[1h09]] – bLys – bacteriophage CP-1<br />
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[[1oba]] – bLys + choline<br />
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[[2ixu]] – bLys + peptidoglycan analog<br />
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[[2ixv]], [[2j8f]], [[2j8g]] – bLys (mutant) + peptidoglycan analog<br />
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[[2mk5]] – GH15Lys residues 368-495 – phage GH15 – NMR<br />
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[[4olk]] – GH15Lys CHAP domain residues 1-165<br />
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[[4ols]] – GH15Lys amidase domain residues 165-403<br />
</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

Revision as of 11:45, 31 January 2016

Abalone lysin (PDB code 1lis)

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References

  1. Shaw A, McRee DE, Vacquier VD, Stout CD. The crystal structure of lysin, a fertilization protein. Science. 1993 Dec 17;262(5141):1864-7. PMID:8266073
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