5hkl

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'''Unreleased structure'''
 
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The entry 5hkl is ON HOLD until Paper Publication
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==Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with inorganic phosphate==
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<StructureSection load='5hkl' size='340' side='right' caption='[[5hkl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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Authors: Donini, S., Bolognesi, G., Rizzi, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5hkl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HKL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HKL FirstGlance]. <br>
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Description: Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with inorganic phosphate
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hkl OCA], [http://pdbe.org/5hkl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hkl RCSB], [http://www.ebi.ac.uk/pdbsum/5hkl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hkl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PYRE_MYCTU PYRE_MYCTU]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
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__TOC__
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</StructureSection>
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[[Category: Orotate phosphoribosyltransferase]]
[[Category: Bolognesi, G]]
[[Category: Bolognesi, G]]
[[Category: Donini, S]]
[[Category: Donini, S]]
[[Category: Rizzi, M]]
[[Category: Rizzi, M]]
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[[Category: De novo pyrimidine nucleotide synthesis]]
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[[Category: Inorganic phosphate complex]]
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[[Category: Oprt]]
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[[Category: Transferase]]

Revision as of 23:41, 25 January 2017

Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with inorganic phosphate

5hkl, resolution 1.90Å

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