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5hs3
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human thymidylate synthase complexed with dUMP and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol== | |
| - | + | <StructureSection load='5hs3' size='340' side='right' caption='[[5hs3]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5hs3]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HS3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KI3:3-AMINO-2-BENZOYL-4-METHYLTHIENO[2,3-B]PYRIDIN-6-OL'>KI3</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hs3 OCA], [http://pdbe.org/5hs3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hs3 RCSB], [http://www.ebi.ac.uk/pdbsum/5hs3 PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Thymidylate synthase]] | ||
| + | [[Category: Almqvist, H]] | ||
| + | [[Category: Artursson, P]] | ||
| + | [[Category: Axelsson, H]] | ||
| + | [[Category: Chen, D]] | ||
| + | [[Category: Haraldsson, M]] | ||
| + | [[Category: Jafari, R]] | ||
[[Category: Larsson, A]] | [[Category: Larsson, A]] | ||
[[Category: Lundback, T]] | [[Category: Lundback, T]] | ||
| - | [[Category: Artursson, P]] | ||
[[Category: Mateus, A]] | [[Category: Mateus, A]] | ||
| - | [[Category: | + | [[Category: Molina, D M]] |
| - | [[Category: | + | [[Category: Nordlund, P]] |
| - | [[Category: | + | [[Category: Nhibitor]] |
| - | [[Category: | + | [[Category: Transferase-transferase inhibitor complex]] |
| - | + | ||
Revision as of 18:22, 26 February 2016
Human thymidylate synthase complexed with dUMP and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol
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