This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4xma
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of the K499G mutant of NanB sialidase from streptococcus pneumoniae in complex with Optactin== | ==Crystal structure of the K499G mutant of NanB sialidase from streptococcus pneumoniae in complex with Optactin== | ||
| - | <StructureSection load='4xma' size='340' side='right' caption='[[4xma]], [[Resolution|resolution]] 2.09Å' scene=''> | + | <StructureSection load='4xma' size='340' side='right'caption='[[4xma]], [[Resolution|resolution]] 2.09Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4xma]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XMA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XMA FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4xma]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XMA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XMA FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=OPX:(1S,3R,4S)-1-[(CYCLOHEXYLAMINO)METHYL]-3,4-DIHYDROXYCYCLOPENTANESULFONIC+ACID'>OPX</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=OPX:(1S,3R,4S)-1-[(CYCLOHEXYLAMINO)METHYL]-3,4-DIHYDROXYCYCLOPENTANESULFONIC+ACID'>OPX</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nanB, SP_1687 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xma OCA], [http://pdbe.org/4xma PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xma RCSB], [http://www.ebi.ac.uk/pdbsum/4xma PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xma OCA], [http://pdbe.org/4xma PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xma RCSB], [http://www.ebi.ac.uk/pdbsum/4xma PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xma ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Sialidase|Sialidase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Exo-alpha-sialidase]] | [[Category: Exo-alpha-sialidase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Strpn]] | ||
[[Category: Brear, P]] | [[Category: Brear, P]] | ||
[[Category: Allosteric inhibitor]] | [[Category: Allosteric inhibitor]] | ||
Revision as of 07:23, 29 May 2019
Crystal structure of the K499G mutant of NanB sialidase from streptococcus pneumoniae in complex with Optactin
| |||||||||||
