1cd8
From Proteopedia
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[[Image:1cd8.jpg|left|200px]] | [[Image:1cd8.jpg|left|200px]] | ||
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'''CRYSTAL STRUCTURE OF A SOLUBLE FORM OF THE HUMAN T CELL CO-RECEPTOR CD8 AT 2.6 ANGSTROMS RESOLUTION''' | '''CRYSTAL STRUCTURE OF A SOLUBLE FORM OF THE HUMAN T CELL CO-RECEPTOR CD8 AT 2.6 ANGSTROMS RESOLUTION''' | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1CD8 is a [[Single protein]] structure | + | 1CD8 is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CD8 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Hendrickson, W A.]] | [[Category: Hendrickson, W A.]] | ||
[[Category: Leahy, D J.]] | [[Category: Leahy, D J.]] | ||
| - | [[Category: | + | [[Category: Surface glycoprotein]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 12:36:06 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 09:36, 2 May 2008
CRYSTAL STRUCTURE OF A SOLUBLE FORM OF THE HUMAN T CELL CO-RECEPTOR CD8 AT 2.6 ANGSTROMS RESOLUTION
Overview
A secreted fragment of the extracellular portion of human CD8 alpha has been expressed in CHO cells, and a deglycosylated and proteolyzed form of this fragment has been crystallized. We report here the crystal structure of this fragment as refined at 2.6 A resolution. The structure was solved by molecular replacement using a superposition of ten variable domains from immunoglobulin light chains as the search model. Only the N-terminal 114 amino acids of CD8 alpha are visible in the electron density maps. The domain formed by these residues possesses a fold typical of immunoglobulin variable domains and associates to form Fv-like homodimers.
About this Structure
1CD8 is a Single protein structure. Full crystallographic information is available from OCA.
Reference
Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 A resolution., Leahy DJ, Axel R, Hendrickson WA, Cell. 1992 Mar 20;68(6):1145-62. PMID:1547508 Page seeded by OCA on Fri May 2 12:36:06 2008
