1cdw
From Proteopedia
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[[Image:1cdw.gif|left|200px]] | [[Image:1cdw.gif|left|200px]] | ||
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'''HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA''' | '''HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA''' | ||
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[[Category: Nikolov, D B.]] | [[Category: Nikolov, D B.]] | ||
[[Category: Roeder, R G.]] | [[Category: Roeder, R G.]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + |
Revision as of 06:40, 24 April 2008
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1cdw, resolution 1.90Å () | |||||||||
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Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
Coordinates: | save as pdb, mmCIF, xml |
HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA
Overview
The TATA box-binding protein (TBP) is required by all three eukaryotic RNA polymerases for correct initiation of transcription of ribosomal, messenger, small nuclear, and transfer RNAs. The cocrystal structure of the C-terminal/core region of human TBP complexed with the TATA element of the adenovirus major late promoter has been determined at 1.9 angstroms resolution. Structural and functional analyses of the protein-DNA complex are presented, with a detailed comparison to our 1.9-angstroms resolution structure of Arabidopsis thaliana TBP2 bound to the same TATA box.
About this Structure
1CDW is a Single protein structure of sequence from Homo sapiens. The following page contains interesting information on the relation of 1CDW with [TATA-Binding Protein]. Full crystallographic information is available from OCA.
Reference
Crystal structure of a human TATA box-binding protein/TATA element complex., Nikolov DB, Chen H, Halay ED, Hoffman A, Roeder RG, Burley SK, Proc Natl Acad Sci U S A. 1996 May 14;93(10):4862-7. PMID:8643494 Page seeded by OCA on Thu Apr 24 09:40:01 2008