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1cdw

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[[Image:1cdw.gif|left|200px]]
[[Image:1cdw.gif|left|200px]]
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{{Structure
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The line below this paragraph, containing "STRUCTURE_1cdw", creates the "Structure Box" on the page.
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
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{{STRUCTURE_1cdw| PDB=1cdw | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cdw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cdw OCA], [http://www.ebi.ac.uk/pdbsum/1cdw PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1cdw RCSB]</span>
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'''HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA'''
'''HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA'''
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[[Category: Nikolov, D B.]]
[[Category: Nikolov, D B.]]
[[Category: Roeder, R G.]]
[[Category: Roeder, R G.]]
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[[Category: complex (transcription factor/dna)]]
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[[Category: Dna binding]]
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[[Category: dna binding]]
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[[Category: Transcription initiation]]
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[[Category: transcription initiation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 24 09:40:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:19:47 2008''
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Revision as of 06:40, 24 April 2008

Image:1cdw.gif


PDB ID 1cdw

Drag the structure with the mouse to rotate
1cdw, resolution 1.90Å ()
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA


Overview

The TATA box-binding protein (TBP) is required by all three eukaryotic RNA polymerases for correct initiation of transcription of ribosomal, messenger, small nuclear, and transfer RNAs. The cocrystal structure of the C-terminal/core region of human TBP complexed with the TATA element of the adenovirus major late promoter has been determined at 1.9 angstroms resolution. Structural and functional analyses of the protein-DNA complex are presented, with a detailed comparison to our 1.9-angstroms resolution structure of Arabidopsis thaliana TBP2 bound to the same TATA box.

About this Structure

1CDW is a Single protein structure of sequence from Homo sapiens. The following page contains interesting information on the relation of 1CDW with [TATA-Binding Protein]. Full crystallographic information is available from OCA.

Reference

Crystal structure of a human TATA box-binding protein/TATA element complex., Nikolov DB, Chen H, Halay ED, Hoffman A, Roeder RG, Burley SK, Proc Natl Acad Sci U S A. 1996 May 14;93(10):4862-7. PMID:8643494 Page seeded by OCA on Thu Apr 24 09:40:01 2008

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