1cmi

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1cmi.gif|left|200px]]
[[Image:1cmi.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1cmi |SIZE=350|CAPTION= <scene name='initialview01'>1cmi</scene>, resolution 2.5&Aring;
+
The line below this paragraph, containing "STRUCTURE_1cmi", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND=
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1cmi| PDB=1cmi | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cmi OCA], [http://www.ebi.ac.uk/pdbsum/1cmi PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1cmi RCSB]</span>
+
-
}}
+
'''STRUCTURE OF THE HUMAN PIN/LC8 DIMER WITH A BOUND PEPTIDE'''
'''STRUCTURE OF THE HUMAN PIN/LC8 DIMER WITH A BOUND PEPTIDE'''
Line 19: Line 16:
==About this Structure==
==About this Structure==
-
1CMI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 1B1W. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMI OCA].
+
1CMI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1b1w 1b1w]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMI OCA].
==Reference==
==Reference==
Line 30: Line 27:
[[Category: Liang, J.]]
[[Category: Liang, J.]]
[[Category: Snyder, S.]]
[[Category: Snyder, S.]]
-
[[Category: dynein light chain]]
+
[[Category: Dynein light chain]]
-
[[Category: lc8]]
+
[[Category: Lc8]]
-
[[Category: nno]]
+
[[Category: Nno]]
-
[[Category: pin]]
+
[[Category: Pin]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 12:53:33 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:24:26 2008''
+

Revision as of 09:53, 2 May 2008

Image:1cmi.gif

Template:STRUCTURE 1cmi

STRUCTURE OF THE HUMAN PIN/LC8 DIMER WITH A BOUND PEPTIDE


Overview

The structure of the protein known both as neuronal nitric oxide synthase inhibitory protein, PIN (protein inhibitor of nNOS), and also as the 8 kDa dynein light chain (LC8) has been solved by X-ray diffraction. Two PIN/LC8 monomers related by a two-fold axis form a rectangular dimer. Two pairs of alpha-helices cover opposite faces, and each pair of helices packs against a beta-sheet with five antiparallel beta-strands. Each five-stranded beta-sheet contains four strands from one monomer and a fifth strand from the other monomer. A 13-residue peptide from nNOS is bound to the dimer in a deep hydrophobic groove as a sixth antiparallel beta-strand. The structure provides key insights into dimerization of and peptide binding by the multifunctional PIN/LC8 protein.

About this Structure

1CMI is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1b1w. Full crystallographic information is available from OCA.

Reference

Structure of the PIN/LC8 dimer with a bound peptide., Liang J, Jaffrey SR, Guo W, Snyder SH, Clardy J, Nat Struct Biol. 1999 Aug;6(8):735-40. PMID:10426949 Page seeded by OCA on Fri May 2 12:53:33 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1cmi"
Personal tools