DNA glycosylase

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Line 40: Line 40:
**[[1wei]], [[1mud]] - EcADG catalytic domain (mutant) + adenine<br />
**[[1wei]], [[1mud]] - EcADG catalytic domain (mutant) + adenine<br />
-
**[[3fsp]], [[3fsq]] – GsADG + DNA – ''Geobacillus stearothermophilus''<BR />
+
**[[3fsp]], [[5dpk]] – GsADG + DNA – ''Geobacillus stearothermophilus''<BR />
**[[3g0q]], [[1vrl]], [[1rrq]], [[1rrs]] - GsADG (mutant) + DNA <BR />
**[[3g0q]], [[1vrl]], [[1rrq]], [[1rrs]] - GsADG (mutant) + DNA <BR />
Line 49: Line 49:
**[[1akz]], [[3tkb]] - hUDG (mutant) <BR />
**[[1akz]], [[3tkb]] - hUDG (mutant) <BR />
**[[2jhq]] – UDG – ''Vibrio cholerae''<BR />
**[[2jhq]] – UDG – ''Vibrio cholerae''<BR />
-
**[[2owq]], [[2owr]], [[3nt7]], [[4dof]], [[4dog]], [[4rib]], [[4lzb]] – UDG (mutant) – Vaccinia virus<BR />
+
**[[2owq]], [[5jx3]], [[3nt7]], [[4dof]], [[4dog]], [[4rib]], [[4lzb]] – UDG (mutant) – Vaccinia virus<BR />
**[[2d3y]], [[1ui0]], [[1ui1]] – TtUDG – ''Thermus thermophilus''<BR />
**[[2d3y]], [[1ui0]], [[1ui1]] – TtUDG – ''Thermus thermophilus''<BR />
**[[1lqj]] – EcUDG<BR />
**[[1lqj]] – EcUDG<BR />

Revision as of 10:03, 16 November 2016

Structure of adenine DNA glycosylase containing Fe4S4 cluster complex with DNA containing an oxoG base, deoxy-ribofuranose phosphate and Ca+2 ion (green) (PDB code 1rrs).

Drag the structure with the mouse to rotate

3D Structures of DNA glycosylate

Updated on 16-November-2016

References

  1. Fromme JC, Banerjee A, Verdine GL. DNA glycosylase recognition and catalysis. Curr Opin Struct Biol. 2004 Feb;14(1):43-9. PMID:15102448 doi:http://dx.doi.org/10.1016/j.sbi.2004.01.003
  2. Fromme JC, Banerjee A, Huang SJ, Verdine GL. Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase. Nature. 2004 Feb 12;427(6975):652-6. PMID:14961129 doi:10.1038/nature02306

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Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky

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